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Post-translational modification: nature’s escape from genetic imprisonment and the basis for dynamic information encoding

We discuss protein post-translational modification (PTM) from an information processing perspective. PTM at multiple sites on a protein creates a combinatorial explosion in the number of potential “mod-forms”, or global patterns of modification. Distinct mod-forms can elicit distinct downstream resp...

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Bibliografiske detaljer
Main Authors: Prabakaran, Sudhakaran, Lippens, Guy, Steen, Hanno, Gunawardena, Jeremy
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473174/
https://ncbi.nlm.nih.gov/pubmed/22899623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wsbm.1185
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