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Functional polymorphisms in the insulin-like binding protein-3 gene may modulate susceptibility to differentiated thyroid carcinoma in Caucasian Americans

PURPOSE: The insulin-like growth factor (IGF) pathway is believed to play a pivotal role in thyroid carcinogenesis. Polymorphisms of IGF-1 and IGF binding protein-3 (IGFBP-3) have been associated with modulation of risk for the emergence of assorted common malignancies, but studies of the influence...

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Detalhes bibliográficos
Main Authors: Xu, Li, Mugartegui, Liliana, Li, Guojun, Sarlis, Nicholas J., Wei, Qingyi, Zafereo, Mark E., Sturgis, Erich M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473095/
https://ncbi.nlm.nih.gov/pubmed/22415807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.21900
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