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Significance of MDM2 and P14(ARF) polymorphisms in susceptibility to differentiated thyroid carcinoma
BACKGROUND: Murine double minute 2 (MDM2) oncoprotein and p14(ARF) tumor suppressor play pivotal roles in regulating p53 and function in the MAPK pathway, which is frequently mutated in differentiated thyroid carcinoma (DTC). We hypothesized that functional polymorphisms in the promoters of MDM2 and...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3610784/ https://ncbi.nlm.nih.gov/pubmed/23218882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2012.11.009 |
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