The Ionic and Hydrophobic Interactions Are Required for the Auto Activation of Cysteine Proteases of Plasmodium falciparum

The Plasmodium falciparum cysteine proteases falcipain-2 and falcipain-3 are major hemoglobinases and potential antimalarial drug targets. Our previous studies demonstrated that these enzymes are equipped with specific domains for specific functions. Structural and functional analysis of falcipains...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sundararaj, Srinivasan, Singh, Deepak, Saxena, Ajay K., Vashisht, Kapil, Sijwali, Puran S., Dixit, Rajnikant, Pandey, Kailash C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473063/
https://ncbi.nlm.nih.gov/pubmed/23077573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047227
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