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Replacement of anticodon loop nucleotides to produce functional tRNAs: amber suppressors derived from yeast tRNAPhe.

The method of anticodon loop replacement has been used to make derivatives of yeast tRNAPhe. By constructing tRNAs with a CUA anticodon, complementary to the amber (UAG) terminator, functional amber suppressor tRNAs were produced. The activity of these tRNAs was assayed in a mammalian cell-free prot...

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Библиографические подробности
Главные авторы: Bruce, A G, Atkins, J F, Wills, N, Uhlenbeck, O, Gesteland, R F
Формат: Artigo
Язык:Inglês
Опубликовано: 1982
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC347291/
https://ncbi.nlm.nih.gov/pubmed/6961400
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