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Common Fragile Sites: Genomic Hotspots of DNA Damage and Carcinogenesis
Genomic instability, a hallmark of cancer, occurs preferentially at specific genomic regions known as common fragile sites (CFSs). CFSs are evolutionarily conserved and late replicating regions with AT-rich sequences, and CFS instability is correlated with cancer. In the last decade, much progress h...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Molecular Diversity Preservation International (MDPI)
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3472787/ https://ncbi.nlm.nih.gov/pubmed/23109895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms130911974 |
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