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BLM prevents instability of structure-forming DNA sequences at common fragile sites
Genome instability often arises at common fragile sites (CFSs) leading to cancer-associated chromosomal rearrangements. However, the underlying mechanisms of how CFS protection is achieved is not well understood. We demonstrate that BLM plays an important role in the maintenance of genome stability...
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| Publicado no: | PLoS Genet |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6289451/ https://ncbi.nlm.nih.gov/pubmed/30496191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007816 |
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