Induction of Anti-Tumor Immunity Ex Vivo Using Dendritic Cells Transduced with Fowl Pox Vector Expressing MUC1, CEA, and a Triad of Costimulatory Molecules (rF-PANVAC)()

The fowl pox vector expressing the tumor associated antigens MUC1 and CEA in the context of costimulatory molecules (rF-PANVAC) has shown promise as a tumor vaccine. However, vaccine mediated expansion of suppressor T cell populations may blunt clinical efficacy. We characterized the cellular immune...

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Hauptverfasser: Vasir, Baldev, Zarwan, Corrine, Ahmad, Rehan, Crawford, Keith D, Rajabi, Hassan, Matsuoka, Ken-Ichi, Rosenblatt, Jacalyn, Wu, Zekui, Mills, Heidi, Kufe, Donald, Avigan, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472644/
https://ncbi.nlm.nih.gov/pubmed/22892452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31826a73de
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