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Torso RTK controls Capicua degradation by changing its subcellular localization

The transcriptional repressor Capicua (Cic) controls multiple aspects of Drosophila embryogenesis and has been implicated in vertebrate development and human diseases. Receptor tyrosine kinases (RTKs) can antagonize Cic-dependent gene repression, but the mechanisms responsible for this effect are no...

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Hlavní autoři: Grimm, Oliver, Zini, Victoria Sanchez, Kim, Yoosik, Casanova, Jordi, Shvartsman, Stanislav Y., Wieschaus, Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472588/
https://ncbi.nlm.nih.gov/pubmed/23048183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.084327
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