Torso RTK controls Capicua degradation by changing its subcellular localization

The transcriptional repressor Capicua (Cic) controls multiple aspects of Drosophila embryogenesis and has been implicated in vertebrate development and human diseases. Receptor tyrosine kinases (RTKs) can antagonize Cic-dependent gene repression, but the mechanisms responsible for this effect are no...

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Bibliographic Details
Main Authors: Grimm, Oliver, Zini, Victoria Sanchez, Kim, Yoosik, Casanova, Jordi, Shvartsman, Stanislav Y., Wieschaus, Eric
Format: Artigo
Language:Inglês
Published: Company of Biologists 2012
Subjects:
Research Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472588/
https://ncbi.nlm.nih.gov/pubmed/23048183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.084327
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