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Torso RTK controls Capicua degradation by changing its subcellular localization

The transcriptional repressor Capicua (Cic) controls multiple aspects of Drosophila embryogenesis and has been implicated in vertebrate development and human diseases. Receptor tyrosine kinases (RTKs) can antagonize Cic-dependent gene repression, but the mechanisms responsible for this effect are no...

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Detalhes bibliográficos
Main Authors: Grimm, Oliver, Zini, Victoria Sanchez, Kim, Yoosik, Casanova, Jordi, Shvartsman, Stanislav Y., Wieschaus, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472588/
https://ncbi.nlm.nih.gov/pubmed/23048183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.084327
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