The Human Rhodopsin Kinase Promoter in an AAV5 Vector Confers Rod- and Cone-Specific Expression in the Primate Retina

Adeno-associated virus (AAV) has proven an effective gene delivery vehicle for the treatment of retinal disease. Ongoing clinical trials using a serotype 2 AAV vector to express RPE65 in the retinal pigment epithelium have proven safe and effective. While many proof-of-concept studies in animal mode...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Boye, Shannon E., Alexander, John J., Boye, Sanford L., Witherspoon, Clark D., Sandefer, Kristen J., Conlon, Thomas J., Erger, Kirsten, Sun, Jingfen, Ryals, Renee, Chiodo, Vince A., Clark, Mark E., Girkin, Christopher A., Hauswirth, William W., Gamlin, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472519/
https://ncbi.nlm.nih.gov/pubmed/22845794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.125
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados