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Mechanisms of Dendritic Cell Lysosomal Killing of Cryptococcus

Cryptococcus neoformans is an opportunistic pulmonary fungal pathogen that disseminates to the CNS causing fatal meningitis in immunocompromised patients. Dendritic cells (DCs) phagocytose C. neoformans following inhalation. Following uptake, cryptococci translocate to the DC lysosomal compartment a...

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Autors principals: Hole, Camaron R., Bui, Hoang, Wormley, Floyd L., Wozniak, Karen L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472389/
https://ncbi.nlm.nih.gov/pubmed/23074646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00739
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