Antifungal Activity of Plasmacytoid Dendritic Cells against Cryptococcus neoformans In Vitro Requires Expression of Dectin-3 (CLEC4D) and Reactive Oxygen Species

Conventional dendritic cells (cDCs) are critical for protection against pulmonary infection with the opportunistic fungal pathogen Cryptococcus neoformans; however, the role of plasmacytoid dendritic cells (pDCs) is unknown. We show for the first time that murine pDCs have direct activity against C....

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Udgivet i:Infect Immun
Main Authors: Hole, Camaron R., Leopold Wager, Chrissy M., Mendiola, Andrew S., Wozniak, Karen L., Campuzano, Althea, Lin, Xin, Wormley, Floyd L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995896/
https://ncbi.nlm.nih.gov/pubmed/27324480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00103-16
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