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Characterization of IL-22 and antimicrobial peptide production in mice protected against pulmonary Cryptococcus neoformans infection

Cryptococcus neoformans is a significant cause of fungal meningitis in patients with impaired T cell-mediated immunity (CMI). Experimental pulmonary infection with a C. neoformans strain engineered to produce IFN-γ, H99γ, results in the induction of Th1-type CMI, resolution of the acute infection, a...

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Bibliografiske detaljer
Main Authors: Wozniak, Karen L., Hole, Camaron R., Yano, Junko, Fidel, Paul L., Wormley, Floyd L.
Format: Artigo
Sprog:Inglês
Udgivet: Society for General Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076872/
https://ncbi.nlm.nih.gov/pubmed/24760968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.073445-0
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