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Immunogenicity when utilizing adenovirus serotype 4 and 5 vaccines expressing circumsporozoite protein in naïve and Adenovirus (Ad5) immune mice

BACKGROUND: Induction of potent long lasting effector T cell responses against liver stage malaria antigens strongly correlates with protection from malaria. While Adenovirus serotype 5 (Ad5) based malaria vaccine platforms have the ability to induce potent effector T cell responses against transgen...

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Autori principali: Schuldt, Nathaniel J, Aldhamen, Yasser A, Godbehere-Roosa, Sarah, Seregin, Sergey S, Kousa, Youssef A, Amalfitano, Andrea
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472263/
https://ncbi.nlm.nih.gov/pubmed/22720732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-209
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