The LCMV gp33-specific memory T cell repertoire narrows with age

BACKGROUND: The memory response to LCMV in mice persists for months to years with only a small decrease in the number of epitope specific CD8 T cells. This long persistence is associated with resistance to lethal LCMV disease. In contrast to studies focused on the number and surface phenotype of the...

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Detalhes bibliográficos
Main Authors: Bunztman, Adam, Vincent, Benjamin G, Krovi, Harsha, Steele, Shaun, Frelinger, Jeffrey A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472190/
https://ncbi.nlm.nih.gov/pubmed/22894656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4933-9-17
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