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Inhibition of formation of complex oligosaccharides by the glucosidase inhibitor bromoconduritol.

The alpha-glucosidase inhibitor bromoconduritol (6-bromo-3,4,5-trihydroxycyclohex-1-ene) inhibits trimming of the innermost glucose residue from the Glc3Man9GlcNAc2 precursor of high-mannose and complex oligosaccharides. This inhibition occurs both in intact cells and with a microsomal enzyme prepar...

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Autores principales: Datema, R, Romero, P A, Legler, G, Schwarz, R T
Formato: Artigo
Lenguaje:Inglês
Publicado: 1982
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC347218/
https://ncbi.nlm.nih.gov/pubmed/6757922
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