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Inhibition of formation of complex oligosaccharides by the glucosidase inhibitor bromoconduritol.

The alpha-glucosidase inhibitor bromoconduritol (6-bromo-3,4,5-trihydroxycyclohex-1-ene) inhibits trimming of the innermost glucose residue from the Glc3Man9GlcNAc2 precursor of high-mannose and complex oligosaccharides. This inhibition occurs both in intact cells and with a microsomal enzyme prepar...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Datema, R, Romero, P A, Legler, G, Schwarz, R T
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347218/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6757922/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.22.6787
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