Effects of the glucosidase inhibitors nojirimycin and deoxynojirimycin on the biosynthesis of membrane and secretory glycoproteins.

The glucosidase inhibitors nojirimycin (NM) and 1-deoxynojirimycin (dNM) interfere with N-linked glycosylation. The effects of NM and dNM on the biosynthesis of secretory glycoproteins (IgD and IgM) and membrane glycoproteins (HLA-A, B, C and -DR antigens) have been examined. Whereas treatment of Ig...

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Bibliographic Details
Published in:EMBO J
Main Authors: Peyrieras, N, Bause, E, Legler, G, Vasilov, R, Claesson, L, Peterson, P, Ploegh, H
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1983
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC555196/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6227481/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1983.tb01509.x
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