Effects of the glucosidase inhibitors nojirimycin and deoxynojirimycin on the biosynthesis of membrane and secretory glycoproteins.

The glucosidase inhibitors nojirimycin (NM) and 1-deoxynojirimycin (dNM) interfere with N-linked glycosylation. The effects of NM and dNM on the biosynthesis of secretory glycoproteins (IgD and IgM) and membrane glycoproteins (HLA-A, B, C and -DR antigens) have been examined. Whereas treatment of Ig...

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Detalhes bibliográficos
Main Authors: Peyrieras, N, Bause, E, Legler, G, Vasilov, R, Claesson, L, Peterson, P, Ploegh, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC555196/
https://ncbi.nlm.nih.gov/pubmed/6227481
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