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Identification and Confirmation of an Exonic Splicing Enhancer Variation in Exon 5 of the Alzheimer Disease Associated PICALM Gene

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by memory and cognitive impairment and is the leading cause of dementia in the elderly. A number of genome wide association studies and subsequent replication studies have been published recently on late onset AD (LOA...

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Detalhes bibliográficos
Main Authors: Schnetz-Boutaud, Nathalie C., Hoffman, Joshua, Coe, Jared E., Murdock, Deborah G., Pericak-Vance, Margaret A., Haines, Jonathan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472126/
https://ncbi.nlm.nih.gov/pubmed/22943764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2012.00727.x
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