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Myosin binding protein-C phosphorylation is the principal mediator of protein kinase A effects on thick filament structure in myocardium

Phosphorylation of cardiac myosin binding protein-C (cMyBP-C) is a regulator of pump function in healthy hearts. However, the mechanisms of regulation by cAMP-dependent protein kinase (PKA)-mediated cMyBP-C phosphorylation have not been completely dissociated from other myofilament substrates for PK...

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Detalhes bibliográficos
Main Authors: Colson, Brett A., Patel, Jitandrakumar R., Chen, Peter P., Bekyarova, Tanya, Abdalla, Mohamed I., Tong, Carl W., Fitzsimons, Daniel P., Irving, Thomas C., Moss, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472100/
https://ncbi.nlm.nih.gov/pubmed/22850286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.07.012
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