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Exo- and endoribonucleolytic activities of yeast cytoplasmic and nuclear RNA exosomes are dependent on the non-catalytic core and central channel
The RNA exosome is an essential multi-subunit ribonuclease (RNase) that contributes to cytoplasmic and nuclear RNA decay and quality control. The nine-subunit exosome core (Exo9) features a prominent central channel formed by stacked asymmetric rings of six RNase PH-like proteins and three S1/KH dom...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3472098/ https://ncbi.nlm.nih.gov/pubmed/22902556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.07.012 |
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