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Exo- and endoribonucleolytic activities of yeast cytoplasmic and nuclear RNA exosomes are dependent on the non-catalytic core and central channel

The RNA exosome is an essential multi-subunit ribonuclease (RNase) that contributes to cytoplasmic and nuclear RNA decay and quality control. The nine-subunit exosome core (Exo9) features a prominent central channel formed by stacked asymmetric rings of six RNase PH-like proteins and three S1/KH dom...

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Autors principals: Wasmuth, Elizabeth V., Lima, Christopher D.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472098/
https://ncbi.nlm.nih.gov/pubmed/22902556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.07.012
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