Substrate discrimination and quality control require each catalytic activity of TRAMP and the nuclear RNA exosome

Quality control requires discrimination between functional and aberrant species to selectively target aberrant substrates for destruction. Nuclear RNA quality control in Saccharomyces cerevisiae includes the TRAMP complex that marks RNA for decay via polyadenylation followed by helicase-dependent 3′...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Das, Mom, Zattas, Dimitrios, Zinder, John C., Wasmuth, Elizabeth V., Henri, Julien, Lima, Christopher D.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8040639/
https://ncbi.nlm.nih.gov/pubmed/33782132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2024846118
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