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Nuclear RNA Surveillance: Role of TRAMP in Controlling Exosome Specificity

The advent of high throughput sequencing technologies has revealed that pervasive transcription generates RNAs from nearly all regions of eukaryotic genomes. Normally these transcripts undergo rapid degradation by a nuclear RNA surveillance system primarily featuring the RNA exosome. This multimeric...

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Detalhes bibliográficos
Main Authors: Schmidt, Karyn, Butler, J. Scott
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578152/
https://ncbi.nlm.nih.gov/pubmed/23417976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wrna.1155
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