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p63RhoGEF: A new switch for G(q) mediated activation of smooth muscle

In normal and diseased vascular smooth muscle (SM), the RhoA pathway, which is activated by multiple agonists through G protein-coupled receptors (GPCRs), plays a central role in regulating basal tone and peripheral resistance. Multiple RhoA GTP exchange factors (GEFs) are expressed in SM raising th...

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Detalhes bibliográficos
Main Authors: Momotani, Ko, Somlyo, A.V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472095/
https://ncbi.nlm.nih.gov/pubmed/22902181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2012.07.007
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