Epigenetic therapy with 3-deazaneplanocin A, an inhibitor of the histone methyltransferase EZH2, inhibits growth of non-small cell lung cancer cells

EZH2 (enhancer of zeste homolog 2) is the catalytic subunit of PRC2 (polycomb repressive complex 2), which mediates histone methyltransferase activity and functions as transcriptional repressor involved in gene silencing. EZH2 is involved in malignant transformation and biological aggressiveness of...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Kikuchi, Junko, Takashina, Taichi, Kinoshita, Ichiro, Kikuchi, Eiki, Shimizu, Yasushi, Sakakibara-Konishi, Jun, Oizumi, Satoshi, Marquez, Victor E., Nishimura, Masaharu, Dosaka-Akita, Hirotoshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472089/
https://ncbi.nlm.nih.gov/pubmed/22925699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2012.08.003
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller