Epigenetic therapy with 3-deazaneplanocin A, an inhibitor of the histone methyltransferase EZH2, inhibits growth of non-small cell lung cancer cells

EZH2 (enhancer of zeste homolog 2) is the catalytic subunit of PRC2 (polycomb repressive complex 2), which mediates histone methyltransferase activity and functions as transcriptional repressor involved in gene silencing. EZH2 is involved in malignant transformation and biological aggressiveness of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kikuchi, Junko, Takashina, Taichi, Kinoshita, Ichiro, Kikuchi, Eiki, Shimizu, Yasushi, Sakakibara-Konishi, Jun, Oizumi, Satoshi, Marquez, Victor E., Nishimura, Masaharu, Dosaka-Akita, Hirotoshi
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472089/
https://ncbi.nlm.nih.gov/pubmed/22925699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2012.08.003
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados