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Specific deletion of glycogen synthase kinase-3β in the renal proximal tubule protects against acute nephrotoxic injury in mice

Renal proximal tubular damage and repair are hallmarks of acute kidney injury. Because glycogen synthase kinase-3β (GSK-3β) is an important cellular regulator of survival and proliferation, we determined its role during injury and recovery of proximal tubules in a mercuric chloride-induced nephrotox...

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Detalhes bibliográficos
Main Authors: Howard, Christiana, Tao, Shixin, Yang, Hai-Chun, Fogo, Agnes B, Woodgett, James R, Harris, Raymond C, Rao, Reena
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472082/
https://ncbi.nlm.nih.gov/pubmed/22785175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2012.239
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