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A dose escalation trial for the combination of erlotinib and sirolimus for recurrent malignant gliomas

In order to achieve higher dosages than previously used in clinical trials, we conducted a phase I trial to determine the maximum tolerated dose (MTD) for the combination of erlotinib and sirolimus for the treatments of recurrent malignant gliomas. Patients with pathologically proven World Health Or...

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Bibliografiske detaljer
Main Authors: Nghiemphu, Phioanh Leia, Lai, Albert, Green, Richard M., Reardon, David A., Cloughesy, Timothy
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472078/
https://ncbi.nlm.nih.gov/pubmed/22918789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-012-0960-y
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