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Imaging biomarkers for antiangiogenic therapy in malignant gliomas

The discovery that malignant gliomas produce an excessive amount of VEGF, a key mediator of angiogenesis, has heightened interest in developing drugs that block angiogenic pathways. These antiangiogenic drugs tend to decrease vascular permeability, thereby diminishing tumor contrast enhancement inde...

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Autori principali: Leu, Kevin, Pope, Whitney B, Cloughesy, Timothy F, Lai, Albert, Nghiemphu, Phioanh L, Chen, Wei, Liau, Linda M, Ellingson, Benjamin M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Future Medicine Ltd 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3932329/
https://ncbi.nlm.nih.gov/pubmed/24570837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/cns.12.29
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