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Formation and repair of pyridyloxobutyl DNA adducts and their relationship to tumor yield in A/J mice
The nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is a known human carcinogen. It generates methyl and pyridyloxobutyl DNA adducts. The role of the methyl DNA adducts has been well-established in the tumorigenic properties of NNK. However, the role of the pyridyloxobutyl DNA adduc...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3472047/ https://ncbi.nlm.nih.gov/pubmed/22928598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300245w |
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