Enterohaemorrhagic Escherichia coli haemolysin is cleaved and inactivated by serine protease EspPα

The haemolysin from enterohaemorrhagic Escherichia coli (EHEC-Hly) and the serine protease EspPα are putative virulence factors of EHEC. We investigated the interplay between these secreted factors and demonstrate that EspPα cleaves the 107 kDa large EHEC-Hly. Degradation was observed when purified...

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Bibliografiske detaljer
Main Authors: Brockmeyer, Jens, Aldick, Thomas, Soltwisch, Jens, Zhang, Wenlan, Tarr, Philip I, Weiss, André, Dreisewerd, Klaus, Müthing, Johannes, Bielaszewska, Martina, Karch, Helge
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2011
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472028/
https://ncbi.nlm.nih.gov/pubmed/21352460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-2920.2011.02431.x
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