Increased Neuronal α-Synuclein Pathology Associates with Its Accumulation in Oligodendrocytes in Mice Modeling α-Synucleinopathies

Multiple system atrophy (MSA) is a progressive neurodegenerative disorder characterized by striatonigral degeneration and olivo-pontocerebellar atrophy. The histopathological hallmark of MSA is glial cytoplasmic inclusions (GCI) within oligodendrocytes, accompanied by neuronal degeneration. MSA is a...

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Autores principales: Kisos, Haya, Pukaß, Katharina, Ben-Hur, Tamir, Richter-Landsberg, Christiane, Sharon, Ronit
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471961/
https://ncbi.nlm.nih.gov/pubmed/23077527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046817
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