5-Fluorouracil Nanoparticles Inhibit Hepatocellular Carcinoma via Activation of the p53 Pathway in the Orthotopic Transplant Mouse Model

Biodegradable polymer nanoparticle drug delivery systems provide targeted drug delivery, improved pharmacokinetic and biodistribution, enhanced drug stability and fewer side effects. These drug delivery systems are widely used for delivering cytotoxic agents. In the present study, we synthesized GC/...

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Autori principali: Cheng, Mingrong, He, Bing, Wan, Tao, Zhu, Weiping, Han, Jiang, Zha, Bingbing, Chen, Houxiang, Yang, Fengxiao, Li, Qing, Wang, Wei, Xu, Hongzhi, Ye, Tao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471936/
https://ncbi.nlm.nih.gov/pubmed/23077553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047115
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