5-Fluorouracil Nanoparticles Inhibit Hepatocellular Carcinoma via Activation of the p53 Pathway in the Orthotopic Transplant Mouse Model

Biodegradable polymer nanoparticle drug delivery systems provide targeted drug delivery, improved pharmacokinetic and biodistribution, enhanced drug stability and fewer side effects. These drug delivery systems are widely used for delivering cytotoxic agents. In the present study, we synthesized GC/...

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Bibliographische Detailangaben
Hauptverfasser: Cheng, Mingrong, He, Bing, Wan, Tao, Zhu, Weiping, Han, Jiang, Zha, Bingbing, Chen, Houxiang, Yang, Fengxiao, Li, Qing, Wang, Wei, Xu, Hongzhi, Ye, Tao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471936/
https://ncbi.nlm.nih.gov/pubmed/23077553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047115
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