5-Fluorouracil Nanoparticles Inhibit Hepatocellular Carcinoma via Activation of the p53 Pathway in the Orthotopic Transplant Mouse Model

Biodegradable polymer nanoparticle drug delivery systems provide targeted drug delivery, improved pharmacokinetic and biodistribution, enhanced drug stability and fewer side effects. These drug delivery systems are widely used for delivering cytotoxic agents. In the present study, we synthesized GC/...

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Main Authors: Cheng, Mingrong, He, Bing, Wan, Tao, Zhu, Weiping, Han, Jiang, Zha, Bingbing, Chen, Houxiang, Yang, Fengxiao, Li, Qing, Wang, Wei, Xu, Hongzhi, Ye, Tao
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471936/
https://ncbi.nlm.nih.gov/pubmed/23077553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047115
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