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Method for Evaluating Multiple Mediators: Mediating Effects of Smoking and COPD on the Association between the CHRNA5-A3 Variant and Lung Cancer Risk

A mediation model explores the direct and indirect effects between an independent variable and a dependent variable by including other variables (or mediators). Mediation analysis has recently been used to dissect the direct and indirect effects of genetic variants on complex diseases using case-con...

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Detalhes bibliográficos
Main Authors: Wang, Jian, Spitz, Margaret R., Amos, Christopher I., Wu, Xifeng, Wetter, David W., Cinciripini, Paul M., Shete, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471886/
https://ncbi.nlm.nih.gov/pubmed/23077662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047705
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