Genetic Variants on 15q25.1, Smoking, and Lung Cancer: An Assessment of Mediation and Interaction

Genome-wide association studies have identified variants on chromosome 15q25.1 that increase the risks of both lung cancer and nicotine dependence and associated smoking behavior. However, there remains debate as to whether the association with lung cancer is direct or is mediated by pathways relate...

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Bibliographic Details
Main Authors: VanderWeele, Tyler J., Asomaning, Kofi, Tchetgen Tchetgen, Eric J., Han, Younghun, Spitz, Margaret R., Shete, Sanjay, Wu, Xifeng, Gaborieau, Valerie, Wang, Ying, McLaughlin, John, Hung, Rayjean J., Brennan, Paul, Amos, Christopher I., Christiani, David C., Lin, Xihong
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353137/
https://ncbi.nlm.nih.gov/pubmed/22306564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwr467
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