Genetic Variants on 15q25.1, Smoking, and Lung Cancer: An Assessment of Mediation and Interaction

Genome-wide association studies have identified variants on chromosome 15q25.1 that increase the risks of both lung cancer and nicotine dependence and associated smoking behavior. However, there remains debate as to whether the association with lung cancer is direct or is mediated by pathways relate...

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Détails bibliographiques
Auteurs principaux: VanderWeele, Tyler J., Asomaning, Kofi, Tchetgen Tchetgen, Eric J., Han, Younghun, Spitz, Margaret R., Shete, Sanjay, Wu, Xifeng, Gaborieau, Valerie, Wang, Ying, McLaughlin, John, Hung, Rayjean J., Brennan, Paul, Amos, Christopher I., Christiani, David C., Lin, Xihong
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2012
Sujets:
Original Contributions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353137/
https://ncbi.nlm.nih.gov/pubmed/22306564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwr467
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