Deletion of the γ-Aminobutyric Acid Transporter 2 (GAT2 and SLC6A13) Gene in Mice Leads to Changes in Liver and Brain Taurine Contents

The GABA transporters (GAT1, GAT2, GAT3, and BGT1) have mostly been discussed in relation to their potential roles in controlling the action of transmitter GABA in the nervous system. We have generated the first mice lacking the GAT2 (slc6a13) gene. Deletion of GAT2 (both mRNA and protein) neither a...

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Detalhes bibliográficos
Main Authors: Zhou, Yun, Holmseth, Silvia, Guo, Caiying, Hassel, Bjørnar, Höfner, Georg, Huitfeldt, Henrik S., Wanner, Klaus T., Danbolt, Niels C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471754/
https://ncbi.nlm.nih.gov/pubmed/22896705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.368175
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