Intracellular Interaction of Interleukin (IL)-32α with Protein Kinase Cϵ (PKCϵ) and STAT3 Protein Augments IL-6 Production in THP-1 Promonocytic Cells

IL-32α is known as a proinflammatory cytokine. However, several evidences implying its action in cells have been recently reported. In this study, we present for the first time that IL-32α plays an intracellular mediatory role in IL-6 production using constitutive expression systems for IL-32α in TH...

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Hlavní autoři: Kang, Jeong-Woo, Park, Yun Sun, Lee, Dong Hun, Kim, Jung-hee, Kim, Man Sub, Bak, Yesol, Hong, Jintae, Yoon, Do-Young
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471736/
https://ncbi.nlm.nih.gov/pubmed/22927445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.400911
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