Interleukin-32α downregulates the activity of the B-cell CLL/lymphoma 6 protein by inhibiting protein kinase Cε-dependent SUMO-2 modification

A proinflammatory cytokine IL-32 acts as an intracellular mediator. IL-32α interacts with many intracellular molecules, but there are no reports of interaction with a transcriptional repressor BCL6. In this study, we showed that PMA induces an interaction between IL-32α, PKCε, and BCL6, forming a tr...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Park, Yun Sun, Kang, Jeong-Woo, Lee, Dong Hun, Kim, Man Sub, Bak, Yesol, Yang, Young, Lee, Hee Gu, Hong, JinTae, Yoon, Do-Young
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226720/
https://ncbi.nlm.nih.gov/pubmed/25245533
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