Interleukin (IL)-32β-mediated CCAAT/Enhancer-binding Protein α (C/EBPα) Phosphorylation by Protein Kinase Cδ (PKCδ) Abrogates the Inhibitory Effect of C/EBPα on IL-10 Production

We previously reported that IL-32β promotes IL-10 production in myeloid cells. However, the underlying mechanism remains elusive. In this study, we demonstrated that IL-32β abrogated the inhibitory effect of CCAAT/enhancer-binding protein α (C/EBPα) on IL-10 expression in U937 cells. We observed tha...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kang, Jeong-Woo, Park, Yun Sun, Kim, Man Sub, Lee, Dong Hun, Bak, Yesol, Ham, Sun Young, Park, Soo Ho, Hong, Jin Tae, Yoon, Do-Young
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2013
Sujets:
Gene Regulation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745311/
https://ncbi.nlm.nih.gov/pubmed/23814099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.465575
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