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Identification of Two-pore Channel 2 as a Novel Regulator of Osteoclastogenesis

Osteoclast differentiation is one of the critical steps that control bone mass levels in osteoporosis, but the molecules involved in osteoclastogenesis are still incompletely understood. Here, we show that two-pore channel 2 (TPC2) is expressed in osteoclast precursor cells, and its knockdown (TPC2-...

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Autores principales: Notomi, Takuya, Ezura, Yoichi, Noda, Masaki
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471725/
https://ncbi.nlm.nih.gov/pubmed/22833668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.328930
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