Mammalian target of rapamycin regulates neutrophil extracellular trap formation via induction of hypoxia-inducible factor 1 alpha

Neutrophils are highly specialized innate immune effector cells that evolved for antimicrobial host defense. In response to inflammatory stimuli and pathogens, they form neutrophil extracellular traps (NETs), which capture and kill extracellular microbes. Deficient NET formation predisposes humans t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: McInturff, Alison M., Cody, Mark J., Elliott, Elizabeth A., Glenn, Jared W., Rowley, Jesse W., Rondina, Matthew T., Yost, Christian C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2012
Schlagworte:
Phagocytes, Granulocytes, and Myelopoiesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471519/
https://ncbi.nlm.nih.gov/pubmed/22919032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-405993
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge