Kruppel-like factor 7 overexpression suppresses hematopoietic stem and progenitor cell function

Increased expression of Kruppel-like factor 7 (KLF7) is an independent predictor of poor outcome in pediatric acute lymphoblastic leukemia. The contribution of KLF7 to hematopoiesis has not been previously described. Herein, we characterized the effect on murine hematopoiesis of the loss of KLF7 and...

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Bibliografiske detaljer
Main Authors: Schuettpelz, Laura G., Gopalan, Priya K., Giuste, Felipe O., Romine, Molly P., van Os, Ronald, Link, Daniel C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2012
Fag:
Hematopoiesis and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471512/
https://ncbi.nlm.nih.gov/pubmed/22936656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-409839
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