Kruppel-like factor 7 overexpression suppresses hematopoietic stem and progenitor cell function

Increased expression of Kruppel-like factor 7 (KLF7) is an independent predictor of poor outcome in pediatric acute lymphoblastic leukemia. The contribution of KLF7 to hematopoiesis has not been previously described. Herein, we characterized the effect on murine hematopoiesis of the loss of KLF7 and...

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Autors principals: Schuettpelz, Laura G., Gopalan, Priya K., Giuste, Felipe O., Romine, Molly P., van Os, Ronald, Link, Daniel C.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2012
Matèries:
Hematopoiesis and Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471512/
https://ncbi.nlm.nih.gov/pubmed/22936656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-409839
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