CD48 on hematopoietic progenitors regulates stem cells and suppresses tumor formation

The proliferation and differentiation of adult stem cells is balanced to ensure adequate generation of differentiated cells, stem cell homeostasis, and guard against malignant transformation. CD48 is broadly expressed on hematopoietic cells but excluded from quiescent long-term murine HSCs. Through...

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Main Authors: Boles, Nathan C., Lin, Kuanyin K., Lukov, Georgi L., Bowman, Teresa V., Baldridge, Megan T., Goodell, Margaret A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2011
Fag:
Hematopoiesis and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139389/
https://ncbi.nlm.nih.gov/pubmed/21576698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-322339
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