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CD48 on hematopoietic progenitors regulates stem cells and suppresses tumor formation

The proliferation and differentiation of adult stem cells is balanced to ensure adequate generation of differentiated cells, stem cell homeostasis, and guard against malignant transformation. CD48 is broadly expressed on hematopoietic cells but excluded from quiescent long-term murine HSCs. Through...

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Auteurs principaux: Boles, Nathan C., Lin, Kuanyin K., Lukov, Georgi L., Bowman, Teresa V., Baldridge, Megan T., Goodell, Margaret A.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139389/
https://ncbi.nlm.nih.gov/pubmed/21576698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-322339
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