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CD48 on hematopoietic progenitors regulates stem cells and suppresses tumor formation

The proliferation and differentiation of adult stem cells is balanced to ensure adequate generation of differentiated cells, stem cell homeostasis, and guard against malignant transformation. CD48 is broadly expressed on hematopoietic cells but excluded from quiescent long-term murine HSCs. Through...

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Detalhes bibliográficos
Main Authors: Boles, Nathan C., Lin, Kuanyin K., Lukov, Georgi L., Bowman, Teresa V., Baldridge, Megan T., Goodell, Margaret A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3139389/
https://ncbi.nlm.nih.gov/pubmed/21576698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-12-322339
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