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The expansion of T-cells and hematopoietic progenitors as a result of overexpression of the Lymphoblastic leukemia gene, Lyl1 can support leukemia formation

This study investigates the function of the Lymphoblastic leukemia gene, Lyl1 in the hematopoietic system and its oncogenic potential in development of leukemia. Overexpression of Lyl1 in mouse bone marrow cells caused T-cell increase in the peripheral blood and expansion of the hematopoietic progen...

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Detalhes bibliográficos
Main Authors: Lukov, Georgi L., Rossi, Lara, Souroullas, George P., Mao, Rui, Goodell, Margaret A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2980862/
https://ncbi.nlm.nih.gov/pubmed/20705338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2010.07.023
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