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Adult Hematopoietic Stem and Progenitor Cells require either Lyl1 or Scl for survival
Scl and Lyl1 encode two related basic-helix-loop-helix transcription factors implicated in T-cell acute lymphoblastic leukemia. Previous studies have shown that Scl is essential for embryonic and adult erythropoiesis whilst Lyl1 is important for B-cell development. Single knockout mice have not reve...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2672304/ https://ncbi.nlm.nih.gov/pubmed/19200805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2009.01.001 |
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